ABCA1 deficiency contributes to podocyte pyroptosis priming via the APE1/IRF1 axis in diabetic kidney disease

Decreased ATP Binding Cassette Transporter A1 (ABCA1) expression and caspase-4-mediated noncanonical inflammasome contribution have been described in podocytes in diabetic kidney disease (DKD). To investigate a link between these pathways, we evaluated pyroptosis-related mediators in human podocytes...

Descripción completa

Detalles Bibliográficos
Autores principales: Ito, Marie, Ducasa, Gloria Michelle, Molina, Judith David, Santos, Javier Varona, Mallela, Shamroop Kumar, Kim, Jin Ju, Ge, Mengyuan, Mitrofanova, Alla, Sloan, Alexis, Merscher, Sandra, Mimura, Imari, Fornoni, Alessia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10267156/
https://www.ncbi.nlm.nih.gov/pubmed/37316538
http://dx.doi.org/10.1038/s41598-023-35499-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10267156/
https://www.ncbi.nlm.nih.gov/pubmed/37316538
http://dx.doi.org/10.1038/s41598-023-35499-5

Ejemplares similares