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ABCA1 deficiency contributes to podocyte pyroptosis priming via the APE1/IRF1 axis in diabetic kidney disease

Decreased ATP Binding Cassette Transporter A1 (ABCA1) expression and caspase-4-mediated noncanonical inflammasome contribution have been described in podocytes in diabetic kidney disease (DKD). To investigate a link between these pathways, we evaluated pyroptosis-related mediators in human podocytes...

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Detalles Bibliográficos
Autores principales:	Ito, Marie, Ducasa, Gloria Michelle, Molina, Judith David, Santos, Javier Varona, Mallela, Shamroop Kumar, Kim, Jin Ju, Ge, Mengyuan, Mitrofanova, Alla, Sloan, Alexis, Merscher, Sandra, Mimura, Imari, Fornoni, Alessia
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10267156/ https://www.ncbi.nlm.nih.gov/pubmed/37316538 http://dx.doi.org/10.1038/s41598-023-35499-5

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