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Regulation of erythroid differentiation in K562 cells by the EPAS1-IRS2 axis under hypoxic conditions
Red blood cells (RBCs) produced in vitro have the potential to alleviate the worldwide demand for blood transfusion. Hematopoietic cell differentiation and proliferation are triggered by numerous cellular physiological processes, including low oxygen concentration (<5%). In addition, hypoxia indu...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10267359/ https://www.ncbi.nlm.nih.gov/pubmed/37325570 http://dx.doi.org/10.3389/fcell.2023.1161541 |