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Drug delivery system for the extended-release of larotrectinib based on a biocompatible Fe-based metal-organic framework: synthesis, characterization, in vitro release properties and antitumor evaluation

Larotrectinib (Lar) is an orally administered tropomyosin receptor kinase (Trk) inhibitor with broad-spectrum antitumor activity that is available in clinical dosage forms as capsules and oral solutions. Currently, corresponding research is focused on developing new extended-release formulation syst...

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Detalles Bibliográficos
Autores principales:	Gan, Lu, Ji, Peng, Zhang, Jin-xiang, Chen, Hao, Yao, Yan-sheng, Ren, Zhen-kun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2023
Materias:	Bioengineering and Biotechnology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10267385/ https://www.ncbi.nlm.nih.gov/pubmed/37324434 http://dx.doi.org/10.3389/fbioe.2023.1197484

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