Triptolide enhances carboplatin-induced apoptosis by inhibiting nucleotide excision repair (NER) activity in melanoma

Introduction: Carboplatin (CBP) is a DNA damaging drug used to treat various cancers, including advanced melanoma. Yet we still face low response rates and short survival due to resistance. Triptolide (TPL) is considered to have multifunctional antitumor effects and has been confirmed to enhance the...

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Detalles Bibliográficos
Autores principales: Wang, Geng, Guo, Hongmin, Ren, Yan, Chen, Weiyi, Wang, Yixuan, Li, Jianing, Liu, Hua, Xing, Jingjun, Zhang, Yanru, Li, Na
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10267402/
https://www.ncbi.nlm.nih.gov/pubmed/37324464
http://dx.doi.org/10.3389/fphar.2023.1157433

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10267402/
https://www.ncbi.nlm.nih.gov/pubmed/37324464
http://dx.doi.org/10.3389/fphar.2023.1157433

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