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Triptolide enhances carboplatin-induced apoptosis by inhibiting nucleotide excision repair (NER) activity in melanoma
Introduction: Carboplatin (CBP) is a DNA damaging drug used to treat various cancers, including advanced melanoma. Yet we still face low response rates and short survival due to resistance. Triptolide (TPL) is considered to have multifunctional antitumor effects and has been confirmed to enhance the...
Autores principales: | Wang, Geng, Guo, Hongmin, Ren, Yan, Chen, Weiyi, Wang, Yixuan, Li, Jianing, Liu, Hua, Xing, Jingjun, Zhang, Yanru, Li, Na |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10267402/ https://www.ncbi.nlm.nih.gov/pubmed/37324464 http://dx.doi.org/10.3389/fphar.2023.1157433 |
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