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Oxidation of caspase-8 by hypothiocyanous acid enables TNF-mediated necroptosis

Necroptosis is a form of regulated cell death triggered by various host and pathogen-derived molecules during infection and inflammation. The essential step leading to necroptosis is phosphorylation of the mixed lineage kinase domain-like protein by receptor-interacting protein kinase 3. Caspase-8 c...

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Detalles Bibliográficos
Autores principales:	Bozonet, Stephanie M., Magon, Nicholas J., Schwartfeger, Abigail J., Konigstorfer, Andreas, Heath, Sarah G., Vissers, Margreet C.M., Morris, Vanessa K., Göbl, Christoph, Murphy, James M., Salvesen, Guy S., Hampton, Mark B.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2023
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10267563/ https://www.ncbi.nlm.nih.gov/pubmed/37150321 http://dx.doi.org/10.1016/j.jbc.2023.104792

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