Cargando…

Inactivation of Minar2 in mice hyperactivates mTOR signaling and results in obesity

OBJECTIVE: Obesity is a complex disorder and is linked to chronic diseases such as type 2 diabetes. Major intrinsically disordered NOTCH2-associated receptor2 (MINAR2) is an understudied protein with an unknown role in obesity and metabolism. The purpose of this study was to determine the impact of...

Descripción completa

Detalles Bibliográficos
Autores principales: Lotfollahzadeh, Saran, Xia, Chaoshuang, Amraei, Razie, Hua, Ning, Kandror, Konstantin V., Farmer, Stephen R., Wei, Wenyi, Costello, Catherine E., Chitalia, Vipul, Rahimi, Nader
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10267597/
https://www.ncbi.nlm.nih.gov/pubmed/37245847
http://dx.doi.org/10.1016/j.molmet.2023.101744