Cargando…
Inactivation of Minar2 in mice hyperactivates mTOR signaling and results in obesity
OBJECTIVE: Obesity is a complex disorder and is linked to chronic diseases such as type 2 diabetes. Major intrinsically disordered NOTCH2-associated receptor2 (MINAR2) is an understudied protein with an unknown role in obesity and metabolism. The purpose of this study was to determine the impact of...
Autores principales: | Lotfollahzadeh, Saran, Xia, Chaoshuang, Amraei, Razie, Hua, Ning, Kandror, Konstantin V., Farmer, Stephen R., Wei, Wenyi, Costello, Catherine E., Chitalia, Vipul, Rahimi, Nader |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10267597/ https://www.ncbi.nlm.nih.gov/pubmed/37245847 http://dx.doi.org/10.1016/j.molmet.2023.101744 |
Ejemplares similares
-
Loss of MINAR2 impairs motor function and causes Parkinson’s disease-like symptoms in mice
por: Ho, Rachel Xi-Yeen, et al.
Publicado: (2020) -
Extracellular vimentin is an attachment factor that facilitates SARS-CoV-2 entry into human endothelial cells
por: Amraei, Razie, et al.
Publicado: (2022) -
PRMT4-mediated arginine methylation promotes tyrosine phosphorylation of VEGFR-2 and regulates filopodia protrusions
por: Hartsough, Edward, et al.
Publicado: (2022) -
COVID-19, Renin-Angiotensin System and Endothelial Dysfunction
por: Amraei, Razie, et al.
Publicado: (2020) -
CD209L/L-SIGN and CD209/DC-SIGN act as receptors for SARS-CoV-2
por: Amraei, Razie, et al.
Publicado: (2021)