Degradomic Identification of Membrane Type 1-Matrix Metalloproteinase as an ADAMTS9 and ADAMTS20 Substrate

The secreted metalloproteases ADAMTS9 and ADAMTS20 are implicated in extracellular matrix proteolysis and primary cilium biogenesis. Here, we show that clonal gene-edited RPE-1 cells in which ADAMTS9 was inactivated, and which constitutively lack ADAMTS20 expression, have morphologic characteristics...

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Detalles Bibliográficos
Autores principales: Nandadasa, Sumeda, Martin, Daniel, Deshpande, Gauravi, Robert, Karyn L., Stack, M. Sharon, Itoh, Yoshifumi, Apte, Suneel S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10267602/
https://www.ncbi.nlm.nih.gov/pubmed/37169079
http://dx.doi.org/10.1016/j.mcpro.2023.100566

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