Termination of STING responses is mediated via ESCRT‐dependent degradation

cGAS‐STING signalling is induced by detection of foreign or mislocalised host double‐stranded (ds)DNA within the cytosol. STING acts as the major signalling hub, where it controls production of type I interferons and inflammatory cytokines. Basally, STING resides on the ER membrane. Following activa...

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Detalles Bibliográficos
Autores principales: Balka, Katherine R, Venkatraman, Rajan, Saunders, Tahnee L, Shoppee, Angus, Pang, Ee Shan, Magill, Zoe, Homman‐Ludiye, Jihane, Huang, Cheng, Lane, Rachael M, York, Harrison M, Tan, Peck, Schittenhelm, Ralf B, Arumugam, Senthil, Kile, Benjamin T, O'Keeffe, Meredith, De Nardo, Dominic
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10267698/
https://www.ncbi.nlm.nih.gov/pubmed/37139896
http://dx.doi.org/10.15252/embj.2022112712

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