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From neurodevelopment to neurodegeneration: utilizing human stem cell models to gain insight into Down syndrome
Down syndrome (DS), caused by triplication of chromosome 21, is the most frequent aneuploidy observed in the human population and represents the most common genetic form of intellectual disability and early-onset Alzheimer’s disease (AD). Individuals with DS exhibit a wide spectrum of clinical prese...
Autores principales: | Watson, L. Ashley, Meharena, Hiruy S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10267712/ https://www.ncbi.nlm.nih.gov/pubmed/37323671 http://dx.doi.org/10.3389/fgene.2023.1198129 |
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