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Using mechanistic models and machine learning to design single-color multiplexed nascent chain tracking experiments
mRNA translation is the ubiquitous cellular process of reading messenger-RNA strands into functional proteins. Over the past decade, large strides in microscopy techniques have allowed observation of mRNA translation at a single-molecule resolution for self-consistent time-series measurements in liv...
Autores principales: | Raymond, William S., Ghaffari, Sadaf, Aguilera, Luis U., Ron, Eric, Morisaki, Tatsuya, Fox, Zachary R., May, Michael P., Stasevich, Timothy J., Munsky, Brian |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10267835/ https://www.ncbi.nlm.nih.gov/pubmed/37325568 http://dx.doi.org/10.3389/fcell.2023.1151318 |
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