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Investigation of adenosine A1 receptor-mediated β-arrestin 2 recruitment using a split-luciferase assay

Background: Adenosine A1 receptor (A(1)AR) plays a prominent role in neurological and cardiac diseases and inflammatory processes. Its endogenous ligand adenosine is known to be one of the key players in the sleep–wake cycle. Like other G protein-coupled receptors (GPCRs), stimulation of A(1)AR lead...

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Detalles Bibliográficos
Autores principales:	Saecker, Luisa, Häberlein, Hanns, Franken, Sebastian
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2023
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10268005/ https://www.ncbi.nlm.nih.gov/pubmed/37324481 http://dx.doi.org/10.3389/fphar.2023.1172551

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