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Use of aortic wall patches as leaflet replacement material during aortic valve repair

OBJECTIVES: Aortic valve repair can be limited by inadequate leaflet tissue for proper coaptation. Various kinds of pericardium have been used for cusp augmentation, but most have failed because of tissue degeneration. A more durable leaflet substitute is needed. METHODS: In this report, 8 consecuti...

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Autores principales: Myers, John L., Clark, J. Brian, James, Timothy W., Downs, Emily, Hasan, Saad M., Binford, Robert S., McNeil, Jeffrey D., Rodriquez, Victor M., Mascio, Christopher E., Wei, Lawrence M., Badhwar, Vinay, Rankin, J. Scott
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10268232/
https://www.ncbi.nlm.nih.gov/pubmed/37324352
http://dx.doi.org/10.1016/j.xjtc.2023.02.017
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author Myers, John L.
Clark, J. Brian
James, Timothy W.
Downs, Emily
Hasan, Saad M.
Binford, Robert S.
McNeil, Jeffrey D.
Rodriquez, Victor M.
Mascio, Christopher E.
Wei, Lawrence M.
Badhwar, Vinay
Rankin, J. Scott
author_facet Myers, John L.
Clark, J. Brian
James, Timothy W.
Downs, Emily
Hasan, Saad M.
Binford, Robert S.
McNeil, Jeffrey D.
Rodriquez, Victor M.
Mascio, Christopher E.
Wei, Lawrence M.
Badhwar, Vinay
Rankin, J. Scott
author_sort Myers, John L.
collection PubMed
description OBJECTIVES: Aortic valve repair can be limited by inadequate leaflet tissue for proper coaptation. Various kinds of pericardium have been used for cusp augmentation, but most have failed because of tissue degeneration. A more durable leaflet substitute is needed. METHODS: In this report, 8 consecutive cases are presented in which autologous ascending aortic tissue was used to augment inadequate native cusps during aortic valve repair. Biologically, aortic wall is a living autologous tissue that could have exceptional durability as a leaflet substitute. Techniques for insertion are described in detail, along with procedural videos. RESULTS: Early surgical outcomes were excellent, with no operative mortalities or complications, and all valves were competent with low valve gradients. Patient follow-up and echocardiograms to a maximum of 8 months’ postrepair remain excellent. CONCLUSIONS: Because of superior biologic characteristics, aortic wall has the potential to provide a better leaflet substitute during aortic valve repair and to expand patient categories amenable to autologous reconstruction. More experience and follow-up should be generated.
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spelling pubmed-102682322023-06-15 Use of aortic wall patches as leaflet replacement material during aortic valve repair Myers, John L. Clark, J. Brian James, Timothy W. Downs, Emily Hasan, Saad M. Binford, Robert S. McNeil, Jeffrey D. Rodriquez, Victor M. Mascio, Christopher E. Wei, Lawrence M. Badhwar, Vinay Rankin, J. Scott JTCVS Tech Adult: Aortic Valve OBJECTIVES: Aortic valve repair can be limited by inadequate leaflet tissue for proper coaptation. Various kinds of pericardium have been used for cusp augmentation, but most have failed because of tissue degeneration. A more durable leaflet substitute is needed. METHODS: In this report, 8 consecutive cases are presented in which autologous ascending aortic tissue was used to augment inadequate native cusps during aortic valve repair. Biologically, aortic wall is a living autologous tissue that could have exceptional durability as a leaflet substitute. Techniques for insertion are described in detail, along with procedural videos. RESULTS: Early surgical outcomes were excellent, with no operative mortalities or complications, and all valves were competent with low valve gradients. Patient follow-up and echocardiograms to a maximum of 8 months’ postrepair remain excellent. CONCLUSIONS: Because of superior biologic characteristics, aortic wall has the potential to provide a better leaflet substitute during aortic valve repair and to expand patient categories amenable to autologous reconstruction. More experience and follow-up should be generated. Elsevier 2023-04-06 /pmc/articles/PMC10268232/ /pubmed/37324352 http://dx.doi.org/10.1016/j.xjtc.2023.02.017 Text en © 2023 The Author(s) https://creativecommons.org/licenses/by/4.0/This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Adult: Aortic Valve
Myers, John L.
Clark, J. Brian
James, Timothy W.
Downs, Emily
Hasan, Saad M.
Binford, Robert S.
McNeil, Jeffrey D.
Rodriquez, Victor M.
Mascio, Christopher E.
Wei, Lawrence M.
Badhwar, Vinay
Rankin, J. Scott
Use of aortic wall patches as leaflet replacement material during aortic valve repair
title Use of aortic wall patches as leaflet replacement material during aortic valve repair
title_full Use of aortic wall patches as leaflet replacement material during aortic valve repair
title_fullStr Use of aortic wall patches as leaflet replacement material during aortic valve repair
title_full_unstemmed Use of aortic wall patches as leaflet replacement material during aortic valve repair
title_short Use of aortic wall patches as leaflet replacement material during aortic valve repair
title_sort use of aortic wall patches as leaflet replacement material during aortic valve repair
topic Adult: Aortic Valve
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10268232/
https://www.ncbi.nlm.nih.gov/pubmed/37324352
http://dx.doi.org/10.1016/j.xjtc.2023.02.017
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