Utilization of 2-nitrophenols in annulations with aryl isothiocyanates towards the synthesis of 2-aminobenzoxazoles

A method for the annulation of 2-nitrophenols with aryl isothiocyanates is reported. The reactions proceeded in the presence of an iron(iii) acetylacetonate catalyst, elemental sulfur, NaOH as a base, and DMSO as a solvent. Derivatives of 2-aminobenzoxazoles bearing nitro, cyano, acetyl, sulfone, se...

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Autores principales: Nguyen, Thanh D., Tran, Danh T., Huynh, Tan N., Ly, Thang M., Nguyen, Tung T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2023
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10269044/
https://www.ncbi.nlm.nih.gov/pubmed/37333726
http://dx.doi.org/10.1039/d3ra02873a
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author Nguyen, Thanh D.
Tran, Danh T.
Huynh, Tan N.
Ly, Thang M.
Nguyen, Tung T.
author_facet Nguyen, Thanh D.
Tran, Danh T.
Huynh, Tan N.
Ly, Thang M.
Nguyen, Tung T.
author_sort Nguyen, Thanh D.
collection PubMed
description A method for the annulation of 2-nitrophenols with aryl isothiocyanates is reported. The reactions proceeded in the presence of an iron(iii) acetylacetonate catalyst, elemental sulfur, NaOH as a base, and DMSO as a solvent. Derivatives of 2-aminobenzoxazoles bearing nitro, cyano, acetyl, sulfone, secondary amine, and pyrrolyl groups were successfully isolated.
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spelling pubmed-102690442023-06-16 Utilization of 2-nitrophenols in annulations with aryl isothiocyanates towards the synthesis of 2-aminobenzoxazoles Nguyen, Thanh D. Tran, Danh T. Huynh, Tan N. Ly, Thang M. Nguyen, Tung T. RSC Adv Chemistry A method for the annulation of 2-nitrophenols with aryl isothiocyanates is reported. The reactions proceeded in the presence of an iron(iii) acetylacetonate catalyst, elemental sulfur, NaOH as a base, and DMSO as a solvent. Derivatives of 2-aminobenzoxazoles bearing nitro, cyano, acetyl, sulfone, secondary amine, and pyrrolyl groups were successfully isolated. The Royal Society of Chemistry 2023-06-15 /pmc/articles/PMC10269044/ /pubmed/37333726 http://dx.doi.org/10.1039/d3ra02873a Text en This journal is © The Royal Society of Chemistry https://creativecommons.org/licenses/by-nc/3.0/
spellingShingle Chemistry
Nguyen, Thanh D.
Tran, Danh T.
Huynh, Tan N.
Ly, Thang M.
Nguyen, Tung T.
Utilization of 2-nitrophenols in annulations with aryl isothiocyanates towards the synthesis of 2-aminobenzoxazoles
title Utilization of 2-nitrophenols in annulations with aryl isothiocyanates towards the synthesis of 2-aminobenzoxazoles
title_full Utilization of 2-nitrophenols in annulations with aryl isothiocyanates towards the synthesis of 2-aminobenzoxazoles
title_fullStr Utilization of 2-nitrophenols in annulations with aryl isothiocyanates towards the synthesis of 2-aminobenzoxazoles
title_full_unstemmed Utilization of 2-nitrophenols in annulations with aryl isothiocyanates towards the synthesis of 2-aminobenzoxazoles
title_short Utilization of 2-nitrophenols in annulations with aryl isothiocyanates towards the synthesis of 2-aminobenzoxazoles
title_sort utilization of 2-nitrophenols in annulations with aryl isothiocyanates towards the synthesis of 2-aminobenzoxazoles
topic Chemistry
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10269044/
https://www.ncbi.nlm.nih.gov/pubmed/37333726
http://dx.doi.org/10.1039/d3ra02873a
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