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Amplicon Deep Sequencing Reveals Multiple Genetic Events Lead to Treatment Failure with Atovaquone-Proguanil in Plasmodium falciparum

Atovaquone-proguanil (AP) is used as treatment for uncomplicated malaria, and as a chemoprophylactic agent against Plasmodium falciparum. Imported malaria remains one of the top causes of fever in Canadian returning travelers. Twelve sequential whole-blood samples before and after AP treatment failu...

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Detalles Bibliográficos
Autores principales:	Castañeda-Mogollón, Daniel, Toppings, Noah B., Kamaliddin, Claire, Lang, Raynell, Kuhn, Susan, Pillai, Dylan R.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Microbiology 2023
Materias:	Mechanisms of Resistance
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10269153/ https://www.ncbi.nlm.nih.gov/pubmed/37154745 http://dx.doi.org/10.1128/aac.01709-22

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