Engineering BioBricks for Deoxysugar Biosynthesis and Generation of New Tetracenomycins

[Image: see text] Tetracenomycins and elloramycins are polyketide natural products produced by several actinomycetes that exhibit antibacterial and anticancer activities. They inhibit ribosomal translation by binding in the polypeptide exit channel of the large ribosomal subunit. The tetracenomycins...

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Detalles Bibliográficos
Autores principales: Tirkkonen, Heli, Brown, Katelyn V., Niemczura, Magdalena, Faudemer, Zélie, Brown, Courtney, Ponomareva, Larissa V., Helmy, Yosra A., Thorson, Jon S., Nybo, S. Eric, Metsä-Ketelä, Mikko, Shaaban, Khaled A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10269268/
https://www.ncbi.nlm.nih.gov/pubmed/37332790
http://dx.doi.org/10.1021/acsomega.3c02460

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