CRISPR Interference-Based Inhibition of MAB_0055c Expression Alters Drug Sensitivity in Mycobacterium abscessus

There is an unmet medical need for effective treatments against Mycobacterium abscessus infections. Although advanced molecular genetic tools to validate drug targets and resistance of M. abscessus exist, the practical design and construction of plasmids are relatively laborious and time-consuming....

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Detalles Bibliográficos
Autores principales: Nguyen, Thanh Quang, Heo, Bo Eun, Park, Yujin, Jeon, Seunghyeon, Choudhary, Arunima, Moon, Cheol, Jang, Jichan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10269454/
https://www.ncbi.nlm.nih.gov/pubmed/37158736
http://dx.doi.org/10.1128/spectrum.00631-23

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10269454/
https://www.ncbi.nlm.nih.gov/pubmed/37158736
http://dx.doi.org/10.1128/spectrum.00631-23

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