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The vanR(Cd) Mutation 343A>G, Resulting in a Thr115Ala Substitution, Is Associated with an Elevated Minimum Inhibitory Concentration (MIC) of Vancomycin in Clostridioides difficile Clinical Isolates from Florida
Clostridioides difficile, the primary cause of nosocomial antibiotic-associated diarrhea, has a complex relationship with antibiotics. While the use of broad-spectrum antibiotics disrupts the gut microbiota and increases the risk of C. difficile infection (CDI), antibiotics are also the primary trea...
Autores principales: | Wickramage, Ishani, Peng, Zhong, Chakraborty, Soumyadeep, Harmanus, Céline, Kuijper, Ed J., Alrabaa, Sally, Smits, Wiep Klaas, Sun, Xingmin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Microbiology
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10269549/ https://www.ncbi.nlm.nih.gov/pubmed/37125917 http://dx.doi.org/10.1128/spectrum.03777-22 |
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