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Characterization of DNA Gyrase Activity and Elucidation of the Impact of Amino Acid Substitution in GyrA on Fluoroquinolone Resistance in Mycobacterium avium

Mycobacterium avium, a member of the M. avium complex (MAC), is the major pathogen contributing to nontuberculous mycobacteria (NTM) infections worldwide. Fluoroquinolones (FQs) are recommended for the treatment of macrolide-resistant MACs. The association of FQ resistance and mutations in the quino...

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Detalles Bibliográficos
Autores principales:	Thapa, Jeewan, Chizimu, Joseph Yamweka, Kitamura, Soyoka, Akapelwa, Mwangala Lonah, Suwanthada, Pondpan, Miura, Nami, Toyting, Jirachaya, Nishimura, Tomoyasu, Hasegawa, Naoki, Nishiuchi, Yukiko, Gordon, Stephen V., Nakajima, Chie, Suzuki, Yasuhiko
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Microbiology 2023
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10269562/ https://www.ncbi.nlm.nih.gov/pubmed/37067420 http://dx.doi.org/10.1128/spectrum.05088-22

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