Characterization of Three Novel IMP Metallo-β-Lactamases, IMP-89, IMP-91, and IMP-96, and Diverse bla(IMP)-Carrying Accessory Genetic Elements from Chinese Clinical Isolates

Three novel imipenemase (IMP)-type metallo-β-lactamases (MBLs), referred to as IMP-89, IMP-91, and IMP-96, were detected in three clinical isolates from China. Antimicrobial susceptibility tests indicated these novel enzymes were resistant to most β-lactams, and IMP-96 with a Ser262Gly mutation had...

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Detalles Bibliográficos
Autores principales: Li, Xinyue, Mu, Xiaofei, Chen, Fangzhou, Lu, Xiuhui, He, Jiaqi, Zheng, Yali, Zhou, Dongsheng, Yin, Zhe, Wang, Peng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10269577/
https://www.ncbi.nlm.nih.gov/pubmed/37092959
http://dx.doi.org/10.1128/spectrum.04986-22

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