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PatA Regulates Isoniazid Resistance by Mediating Mycolic Acid Synthesis and Controls Biofilm Formation by Affecting Lipid Synthesis in Mycobacteria
Lipids are prominent components of the mycobacterial cell wall, and they play critical roles not only in maintaining biofilm formation but also in resisting environmental stress, including drug resistance. However, information regarding the mechanism mediating mycobacterial lipid synthesis remains l...
Autores principales: | Wang, Kun, Deng, Yimin, Cui, Xujie, Chen, Mengli, Ou, Yanzhe, Li, Danting, Guo, Minhao, Li, Weihui |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Microbiology
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10269662/ https://www.ncbi.nlm.nih.gov/pubmed/37212713 http://dx.doi.org/10.1128/spectrum.00928-23 |
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