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PatA Regulates Isoniazid Resistance by Mediating Mycolic Acid Synthesis and Controls Biofilm Formation by Affecting Lipid Synthesis in Mycobacteria

Lipids are prominent components of the mycobacterial cell wall, and they play critical roles not only in maintaining biofilm formation but also in resisting environmental stress, including drug resistance. However, information regarding the mechanism mediating mycobacterial lipid synthesis remains l...

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Detalles Bibliográficos
Autores principales: Wang, Kun, Deng, Yimin, Cui, Xujie, Chen, Mengli, Ou, Yanzhe, Li, Danting, Guo, Minhao, Li, Weihui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10269662/
https://www.ncbi.nlm.nih.gov/pubmed/37212713
http://dx.doi.org/10.1128/spectrum.00928-23

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