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Fatty Acids Abolish Shigella Virulence by Inhibiting Its Master Regulator, VirF

The pathogenicity of Shigella, the intracellular pathogen responsible for human bacillary dysentery, depends on a coordinated and tightly regulated expression of its virulence determinants. This is the result of a cascade organization of its positive regulators, with VirF, a transcriptional activato...

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Detalles Bibliográficos
Autores principales: Trirocco, Rita, Pasqua, Martina, Tramonti, Angela, Grossi, Milena, Colonna, Bianca, Paiardini, Alessandro, Prosseda, Gianni
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10269687/
https://www.ncbi.nlm.nih.gov/pubmed/37140433
http://dx.doi.org/10.1128/spectrum.00778-23