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Fatty Acids Abolish Shigella Virulence by Inhibiting Its Master Regulator, VirF
The pathogenicity of Shigella, the intracellular pathogen responsible for human bacillary dysentery, depends on a coordinated and tightly regulated expression of its virulence determinants. This is the result of a cascade organization of its positive regulators, with VirF, a transcriptional activato...
Autores principales: | Trirocco, Rita, Pasqua, Martina, Tramonti, Angela, Grossi, Milena, Colonna, Bianca, Paiardini, Alessandro, Prosseda, Gianni |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Microbiology
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10269687/ https://www.ncbi.nlm.nih.gov/pubmed/37140433 http://dx.doi.org/10.1128/spectrum.00778-23 |
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