Exosome-Based Multivalent Vaccine: Achieving Potent Immunization, Broadened Reactivity, and Strong T-Cell Responses with Nanograms of Proteins

Currently approved vaccines against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) have focused solely on the spike protein to provide immunity. The first vaccines were developed rapidly using spike mRNA delivered by lipid nanoparticles but required ultralow-temperature storage and hav...

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Detalles Bibliográficos
Autores principales: Cacciottolo, Mafalda, Nice, Justin B, Li, Yujia, LeClaire, Michael J., Twaddle, Ryan, Mora, Ciana L., Adachi, Stephanie Y., Chin, Esther R., Young, Meredith, Angeles, Jenna, Elliott, Kristi, Sun, Minghao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10269692/
https://www.ncbi.nlm.nih.gov/pubmed/37093009
http://dx.doi.org/10.1128/spectrum.00503-23

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