hapE and hmg1 Mutations Are Drivers of cyp51A-Independent Pan-Triazole Resistance in an Aspergillus fumigatus Clinical Isolate

Aspergillus fumigatus is a ubiquitous environmental mold that can cause severe disease in immunocompromised patients and chronic disease in individuals with underlying lung conditions. Triazoles are the most widely used class of antifungal drugs to treat A. fumigatus infections, but their use in the...

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Detalles Bibliográficos
Autores principales: Souza, Ana C. O., Ge, Wenbo, Wiederhold, Nathan P., Rybak, Jeffrey M., Fortwendel, Jarrod R., Rogers, P. David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10269825/
https://www.ncbi.nlm.nih.gov/pubmed/37140376
http://dx.doi.org/10.1128/spectrum.05188-22

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10269825/
https://www.ncbi.nlm.nih.gov/pubmed/37140376
http://dx.doi.org/10.1128/spectrum.05188-22

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