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Liver-Humanized NSG-PiZ Mice Support the Study of Chronic Hepatitis B Virus Infection and Antiviral Therapies

Hepatitis B virus (HBV) is a pathogen of major public health importance that is largely incurable once a chronic infection is established. Only humans and great apes are fully permissive to HBV infection, and this species restriction has impacted HBV research by limiting the utility of small animal...

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Detalles Bibliográficos
Autores principales: Colón-Thillet, Rossana, Stone, Daniel, Loprieno, Michelle A., Klouser, Lindsay, Roychoudhury, Pavitra, Santo, Tracy K., Xie, Hong, Stensland, Laurence, Upham, Sarah L., Pepper, Gregory, Huang, Meei-Li, Aubert, Martine, Jerome, Keith R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10269919/
https://www.ncbi.nlm.nih.gov/pubmed/37199630
http://dx.doi.org/10.1128/spectrum.05176-22