Cargando…
Liver-Humanized NSG-PiZ Mice Support the Study of Chronic Hepatitis B Virus Infection and Antiviral Therapies
Hepatitis B virus (HBV) is a pathogen of major public health importance that is largely incurable once a chronic infection is established. Only humans and great apes are fully permissive to HBV infection, and this species restriction has impacted HBV research by limiting the utility of small animal...
Autores principales: | Colón-Thillet, Rossana, Stone, Daniel, Loprieno, Michelle A., Klouser, Lindsay, Roychoudhury, Pavitra, Santo, Tracy K., Xie, Hong, Stensland, Laurence, Upham, Sarah L., Pepper, Gregory, Huang, Meei-Li, Aubert, Martine, Jerome, Keith R. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Microbiology
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10269919/ https://www.ncbi.nlm.nih.gov/pubmed/37199630 http://dx.doi.org/10.1128/spectrum.05176-22 |
Ejemplares similares
-
Gene editing and elimination of latent herpes simplex virus in vivo
por: Aubert, Martine, et al.
Publicado: (2020) -
CRISPR-Cas9 gene editing of hepatitis B virus in chronically infected humanized mice
por: Stone, Daniel, et al.
Publicado: (2020) -
The E3 Ligase APIP10 Connects the Effector AvrPiz-t to the NLR Receptor Piz-t in Rice
por: Park, Chan Ho, et al.
Publicado: (2016) -
Endotoxin receptor CD14 in PiZ α-1-antitrypsin deficiency individuals
por: Sandström, Caroline S, et al.
Publicado: (2008) -
SERPINA1 PiZ and PiS Heterozygotes and Lung Function Decline in the SAPALDIA Cohort
por: Thun, Gian-Andri, et al.
Publicado: (2012)