Protein kinetics of superoxide dismutase‐1 in familial and sporadic amyotrophic lateral sclerosis

OBJECTIVE: Accumulation of misfolded superoxide dismutase‐1 (SOD1) is a pathological hallmark of SOD1‐related amyotrophic lateral sclerosis (ALS) and is observed in sporadic ALS where its role in pathogenesis is controversial. Understanding in vivo protein kinetics may clarify how SOD1 influences ne...

Descripción completa

Detalles Bibliográficos
Autores principales: Ly, Cindy V., Ireland, Margaret D., Self, Wade K., Bollinger, James, Jockel‐Balsarotti, Jennifer, Herzog, Hillary, Allred, Peggy, Miller, Leah, Doyle, Michael, Anez‐Bruzual, Isabel, Trikamji, Bhavesh, Hyman, Ted, Kung, Tyler, Nicholson, Katherine, Bucelli, Robert C., Patterson, Bruce W., Bateman, Randall J., Miller, Timothy M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10270254/
https://www.ncbi.nlm.nih.gov/pubmed/37119480
http://dx.doi.org/10.1002/acn3.51784

Ejemplares similares

Ejemplares similares