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Annual stability of the plasma Aß40/42 ratio and associated factors

OBJECTIVE: The plasma Aß40/42 ratio is a biomarker of brain amyloidosis. However, the threshold difference between amyloid positivity and negativity is only 10–20% and fluctuates with circadian rhythms, aging, and APOE‐ε4 during the decades of evolution of Alzheimer's disease. METHODS: Plasma A...

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Detalles Bibliográficos
Autores principales: Nakamura, Takumi, Kawarabayashi, Takeshi, Nakahata, Naoko, Itoh, Ken, Ihara, Kazushige, Nakaji, Shigeyuki, Ikeda, Yoshio, Takatama, Masamitsu, Shoji, Mikio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10270258/
https://www.ncbi.nlm.nih.gov/pubmed/37013968
http://dx.doi.org/10.1002/acn3.51770