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Estimating fine age structure and time trends in human contact patterns from coarse contact data: The Bayesian rate consistency model

Since the emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), large-scale social contact surveys are now longitudinally measuring the fundamental changes in human interactions in the face of the pandemic and non-pharmaceutical interventions. Here, we present a model-based Baye...

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Autores principales: Dan, Shozen, Chen, Yu, Chen, Yining, Monod, Melodie, Jaeger, Veronika K., Bhatt, Samir, Karch, André, Ratmann, Oliver
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10270591/
https://www.ncbi.nlm.nih.gov/pubmed/37276210
http://dx.doi.org/10.1371/journal.pcbi.1011191
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author Dan, Shozen
Chen, Yu
Chen, Yining
Monod, Melodie
Jaeger, Veronika K.
Bhatt, Samir
Karch, André
Ratmann, Oliver
author_facet Dan, Shozen
Chen, Yu
Chen, Yining
Monod, Melodie
Jaeger, Veronika K.
Bhatt, Samir
Karch, André
Ratmann, Oliver
author_sort Dan, Shozen
collection PubMed
description Since the emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), large-scale social contact surveys are now longitudinally measuring the fundamental changes in human interactions in the face of the pandemic and non-pharmaceutical interventions. Here, we present a model-based Bayesian approach that can reconstruct contact patterns at 1-year resolution even when the age of the contacts is reported coarsely by 5 or 10-year age bands. This innovation is rooted in population-level consistency constraints in how contacts between groups must add up, which prompts us to call the approach presented here the Bayesian rate consistency model. The model can also quantify time trends and adjust for reporting fatigue emerging in longitudinal surveys through the use of computationally efficient Hilbert Space Gaussian process priors. We illustrate estimation accuracy on simulated data as well as social contact data from Europe and Africa for which the exact age of contacts is reported, and then apply the model to social contact data with coarse information on the age of contacts that were collected in Germany during the COVID-19 pandemic from April to June 2020 across five longitudinal survey waves. We estimate the fine age structure in social contacts during the early stages of the pandemic and demonstrate that social contact intensities rebounded in an age-structured, non-homogeneous manner. The Bayesian rate consistency model provides a model-based, non-parametric, computationally tractable approach for estimating the fine structure and longitudinal trends in social contacts and is applicable to contemporary survey data with coarsely reported age of contacts as long as the exact age of survey participants is reported.
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spelling pubmed-102705912023-06-16 Estimating fine age structure and time trends in human contact patterns from coarse contact data: The Bayesian rate consistency model Dan, Shozen Chen, Yu Chen, Yining Monod, Melodie Jaeger, Veronika K. Bhatt, Samir Karch, André Ratmann, Oliver PLoS Comput Biol Research Article Since the emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), large-scale social contact surveys are now longitudinally measuring the fundamental changes in human interactions in the face of the pandemic and non-pharmaceutical interventions. Here, we present a model-based Bayesian approach that can reconstruct contact patterns at 1-year resolution even when the age of the contacts is reported coarsely by 5 or 10-year age bands. This innovation is rooted in population-level consistency constraints in how contacts between groups must add up, which prompts us to call the approach presented here the Bayesian rate consistency model. The model can also quantify time trends and adjust for reporting fatigue emerging in longitudinal surveys through the use of computationally efficient Hilbert Space Gaussian process priors. We illustrate estimation accuracy on simulated data as well as social contact data from Europe and Africa for which the exact age of contacts is reported, and then apply the model to social contact data with coarse information on the age of contacts that were collected in Germany during the COVID-19 pandemic from April to June 2020 across five longitudinal survey waves. We estimate the fine age structure in social contacts during the early stages of the pandemic and demonstrate that social contact intensities rebounded in an age-structured, non-homogeneous manner. The Bayesian rate consistency model provides a model-based, non-parametric, computationally tractable approach for estimating the fine structure and longitudinal trends in social contacts and is applicable to contemporary survey data with coarsely reported age of contacts as long as the exact age of survey participants is reported. Public Library of Science 2023-06-05 /pmc/articles/PMC10270591/ /pubmed/37276210 http://dx.doi.org/10.1371/journal.pcbi.1011191 Text en © 2023 Dan et al https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Research Article
Dan, Shozen
Chen, Yu
Chen, Yining
Monod, Melodie
Jaeger, Veronika K.
Bhatt, Samir
Karch, André
Ratmann, Oliver
Estimating fine age structure and time trends in human contact patterns from coarse contact data: The Bayesian rate consistency model
title Estimating fine age structure and time trends in human contact patterns from coarse contact data: The Bayesian rate consistency model
title_full Estimating fine age structure and time trends in human contact patterns from coarse contact data: The Bayesian rate consistency model
title_fullStr Estimating fine age structure and time trends in human contact patterns from coarse contact data: The Bayesian rate consistency model
title_full_unstemmed Estimating fine age structure and time trends in human contact patterns from coarse contact data: The Bayesian rate consistency model
title_short Estimating fine age structure and time trends in human contact patterns from coarse contact data: The Bayesian rate consistency model
title_sort estimating fine age structure and time trends in human contact patterns from coarse contact data: the bayesian rate consistency model
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10270591/
https://www.ncbi.nlm.nih.gov/pubmed/37276210
http://dx.doi.org/10.1371/journal.pcbi.1011191
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