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Diagnostic Accuracy of Imaging Devices in Glaucoma: An Updated Meta-Analysis

BACKGROUND: Different devices have diverse accuracy in diagnosing glaucoma, and therefore choosing the best device is challenging. Thereby, this study was conducted to evaluate the diagnostic sensitivity and specificity of imaging devices in glaucoma and explore the need for an updated meta-analysis...

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Autores principales: Moradi, Yousef, Moradkhani, Asra, Pourazizi, Mohsen, Rezaei, Leila, Azami, Mobin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Iran University of Medical Sciences 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10270645/
https://www.ncbi.nlm.nih.gov/pubmed/37332389
http://dx.doi.org/10.47176/mjiri.37.38
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author Moradi, Yousef
Moradkhani, Asra
Pourazizi, Mohsen
Rezaei, Leila
Azami, Mobin
author_facet Moradi, Yousef
Moradkhani, Asra
Pourazizi, Mohsen
Rezaei, Leila
Azami, Mobin
author_sort Moradi, Yousef
collection PubMed
description BACKGROUND: Different devices have diverse accuracy in diagnosing glaucoma, and therefore choosing the best device is challenging. Thereby, this study was conducted to evaluate the diagnostic sensitivity and specificity of imaging devices in glaucoma and explore the need for an updated meta-analysis on this issue. METHODS: In this systematic review and meta-analysis, PubMed, Scopus, and Web of Science databases were searched for articles published between January 2004 and 2022. Cross-sectional or diagnostic studies were selected, and sensitivity, specificity, positive predictive value, and negative predictive value were measured. RESULTS: A total of 28 cross-sectional studies were included for meta-analysis. Devices were divided into 2 groups, based on the optic nerve area and the macular area. For the nerve area, the pooled sensitivity was 77% (CI 95%, 70-83; I2, 90.01%) and the pooled specificity was 89% (CI 95%, 84-92, I2, 93.22%), and for the macular area, the pooled sensitivity was 87% (CI 95%, 80-92, I2, 91.79%), and the pooled specificity was 90% (CI 95%, 84-94; I2, 86.30%). We analyzed each device separately. For optical coherence tomography(OCT), the pooled sensitivity was 85% (CI 95%, 81-89; I2, 87.82%) and the pooled specificity was 89% (CI 95%, 85-92; I2, 84.39%); for Heidelberg retinal tomography (HRT), the pooled sensitivity was 72% (CI 95%, 57-83; I2, 88.94%) and the pooled specificity was 79% (CI 95%, 62-90; I2, 98.61%), and for optical coherence tomography angiography (OCTA), the pooled sensitivity was 82% (CI 95%, 66-91; I2, 93.71%) and the pooled specificity was 93% (CI 95%, 87-96; I2, 64.72%). CONCLUSION: The macular area was more sensitive and specific than the optic nerve head. Furthermore, OCT had higher sensitivity, and OCTA had higher specificity when compared with other imaging devices.
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spelling pubmed-102706452023-06-16 Diagnostic Accuracy of Imaging Devices in Glaucoma: An Updated Meta-Analysis Moradi, Yousef Moradkhani, Asra Pourazizi, Mohsen Rezaei, Leila Azami, Mobin Med J Islam Repub Iran Original Article BACKGROUND: Different devices have diverse accuracy in diagnosing glaucoma, and therefore choosing the best device is challenging. Thereby, this study was conducted to evaluate the diagnostic sensitivity and specificity of imaging devices in glaucoma and explore the need for an updated meta-analysis on this issue. METHODS: In this systematic review and meta-analysis, PubMed, Scopus, and Web of Science databases were searched for articles published between January 2004 and 2022. Cross-sectional or diagnostic studies were selected, and sensitivity, specificity, positive predictive value, and negative predictive value were measured. RESULTS: A total of 28 cross-sectional studies were included for meta-analysis. Devices were divided into 2 groups, based on the optic nerve area and the macular area. For the nerve area, the pooled sensitivity was 77% (CI 95%, 70-83; I2, 90.01%) and the pooled specificity was 89% (CI 95%, 84-92, I2, 93.22%), and for the macular area, the pooled sensitivity was 87% (CI 95%, 80-92, I2, 91.79%), and the pooled specificity was 90% (CI 95%, 84-94; I2, 86.30%). We analyzed each device separately. For optical coherence tomography(OCT), the pooled sensitivity was 85% (CI 95%, 81-89; I2, 87.82%) and the pooled specificity was 89% (CI 95%, 85-92; I2, 84.39%); for Heidelberg retinal tomography (HRT), the pooled sensitivity was 72% (CI 95%, 57-83; I2, 88.94%) and the pooled specificity was 79% (CI 95%, 62-90; I2, 98.61%), and for optical coherence tomography angiography (OCTA), the pooled sensitivity was 82% (CI 95%, 66-91; I2, 93.71%) and the pooled specificity was 93% (CI 95%, 87-96; I2, 64.72%). CONCLUSION: The macular area was more sensitive and specific than the optic nerve head. Furthermore, OCT had higher sensitivity, and OCTA had higher specificity when compared with other imaging devices. Iran University of Medical Sciences 2023-04-15 /pmc/articles/PMC10270645/ /pubmed/37332389 http://dx.doi.org/10.47176/mjiri.37.38 Text en © 2023 Iran University of Medical Sciences https://creativecommons.org/licenses/by-nc-sa/1.0/This is an open-access article distributed under the terms of the Creative Commons Attribution NonCommercial-ShareAlike 1.0 License (CC BY-NC-SA 1.0), which allows users to read, copy, distribute and make derivative works for non-commercial purposes from the material, as long as the author of the original work is cited properly.
spellingShingle Original Article
Moradi, Yousef
Moradkhani, Asra
Pourazizi, Mohsen
Rezaei, Leila
Azami, Mobin
Diagnostic Accuracy of Imaging Devices in Glaucoma: An Updated Meta-Analysis
title Diagnostic Accuracy of Imaging Devices in Glaucoma: An Updated Meta-Analysis
title_full Diagnostic Accuracy of Imaging Devices in Glaucoma: An Updated Meta-Analysis
title_fullStr Diagnostic Accuracy of Imaging Devices in Glaucoma: An Updated Meta-Analysis
title_full_unstemmed Diagnostic Accuracy of Imaging Devices in Glaucoma: An Updated Meta-Analysis
title_short Diagnostic Accuracy of Imaging Devices in Glaucoma: An Updated Meta-Analysis
title_sort diagnostic accuracy of imaging devices in glaucoma: an updated meta-analysis
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10270645/
https://www.ncbi.nlm.nih.gov/pubmed/37332389
http://dx.doi.org/10.47176/mjiri.37.38
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