Maternal Breast Milk Secretor Phenotype Does Not Affect Infant Susceptibility to Rotavirus Diarrhea

Breast milk secretor status is associated with antibody seroconversion to oral rotavirus vaccination. Here, we were unable to detect a similar impact on risk of infant rotavirus diarrhea or vaccine efficacy through 2 years of life, underscoring limitations of immunogenicity assessment alone in evalu...

Descripción completa

Detalles Bibliográficos
Autores principales: Williams, Frank B, Kader, Md Abdul, Dickson, Dorothy M, Colgate, E Ross, Alam, Masud, Haque, Rashidul, Petri, William A, Kirkpatrick, Beth D, Lee, Benjamin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Brief Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10270652/
https://www.ncbi.nlm.nih.gov/pubmed/37333724
http://dx.doi.org/10.1093/ofid/ofad299
_version_ 1785059362688991232
author Williams, Frank B
Kader, Md Abdul
Dickson, Dorothy M
Colgate, E Ross
Alam, Masud
Haque, Rashidul
Petri, William A
Kirkpatrick, Beth D
Lee, Benjamin
author_facet Williams, Frank B
Kader, Md Abdul
Dickson, Dorothy M
Colgate, E Ross
Alam, Masud
Haque, Rashidul
Petri, William A
Kirkpatrick, Beth D
Lee, Benjamin
author_sort Williams, Frank B
collection PubMed
description Breast milk secretor status is associated with antibody seroconversion to oral rotavirus vaccination. Here, we were unable to detect a similar impact on risk of infant rotavirus diarrhea or vaccine efficacy through 2 years of life, underscoring limitations of immunogenicity assessment alone in evaluation of oral rotavirus vaccine response.
format Online
Article
Text
id pubmed-10270652
institution National Center for Biotechnology Information
language English
publishDate 2023
publisher Oxford University Press
record_format MEDLINE/PubMed
spelling pubmed-102706522023-06-16 Maternal Breast Milk Secretor Phenotype Does Not Affect Infant Susceptibility to Rotavirus Diarrhea Williams, Frank B Kader, Md Abdul Dickson, Dorothy M Colgate, E Ross Alam, Masud Haque, Rashidul Petri, William A Kirkpatrick, Beth D Lee, Benjamin Open Forum Infect Dis Brief Report Breast milk secretor status is associated with antibody seroconversion to oral rotavirus vaccination. Here, we were unable to detect a similar impact on risk of infant rotavirus diarrhea or vaccine efficacy through 2 years of life, underscoring limitations of immunogenicity assessment alone in evaluation of oral rotavirus vaccine response. Oxford University Press 2023-06-07 /pmc/articles/PMC10270652/ /pubmed/37333724 http://dx.doi.org/10.1093/ofid/ofad299 Text en © The Author(s) 2023. Published by Oxford University Press on behalf of Infectious Diseases Society of America. https://creativecommons.org/licenses/by/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Brief Report
Williams, Frank B
Kader, Md Abdul
Dickson, Dorothy M
Colgate, E Ross
Alam, Masud
Haque, Rashidul
Petri, William A
Kirkpatrick, Beth D
Lee, Benjamin
Maternal Breast Milk Secretor Phenotype Does Not Affect Infant Susceptibility to Rotavirus Diarrhea
title Maternal Breast Milk Secretor Phenotype Does Not Affect Infant Susceptibility to Rotavirus Diarrhea
title_full Maternal Breast Milk Secretor Phenotype Does Not Affect Infant Susceptibility to Rotavirus Diarrhea
title_fullStr Maternal Breast Milk Secretor Phenotype Does Not Affect Infant Susceptibility to Rotavirus Diarrhea
title_full_unstemmed Maternal Breast Milk Secretor Phenotype Does Not Affect Infant Susceptibility to Rotavirus Diarrhea
title_short Maternal Breast Milk Secretor Phenotype Does Not Affect Infant Susceptibility to Rotavirus Diarrhea
title_sort maternal breast milk secretor phenotype does not affect infant susceptibility to rotavirus diarrhea
topic Brief Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10270652/
https://www.ncbi.nlm.nih.gov/pubmed/37333724
http://dx.doi.org/10.1093/ofid/ofad299
work_keys_str_mv AT williamsfrankb maternalbreastmilksecretorphenotypedoesnotaffectinfantsusceptibilitytorotavirusdiarrhea
AT kadermdabdul maternalbreastmilksecretorphenotypedoesnotaffectinfantsusceptibilitytorotavirusdiarrhea
AT dicksondorothym maternalbreastmilksecretorphenotypedoesnotaffectinfantsusceptibilitytorotavirusdiarrhea
AT colgateeross maternalbreastmilksecretorphenotypedoesnotaffectinfantsusceptibilitytorotavirusdiarrhea
AT alammasud maternalbreastmilksecretorphenotypedoesnotaffectinfantsusceptibilitytorotavirusdiarrhea
AT haquerashidul maternalbreastmilksecretorphenotypedoesnotaffectinfantsusceptibilitytorotavirusdiarrhea
AT petriwilliama maternalbreastmilksecretorphenotypedoesnotaffectinfantsusceptibilitytorotavirusdiarrhea
AT kirkpatrickbethd maternalbreastmilksecretorphenotypedoesnotaffectinfantsusceptibilitytorotavirusdiarrhea
AT leebenjamin maternalbreastmilksecretorphenotypedoesnotaffectinfantsusceptibilitytorotavirusdiarrhea

Ejemplares similares