Cargando…
Maternal Breast Milk Secretor Phenotype Does Not Affect Infant Susceptibility to Rotavirus Diarrhea
Breast milk secretor status is associated with antibody seroconversion to oral rotavirus vaccination. Here, we were unable to detect a similar impact on risk of infant rotavirus diarrhea or vaccine efficacy through 2 years of life, underscoring limitations of immunogenicity assessment alone in evalu...
Autores principales: | , , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10270652/ https://www.ncbi.nlm.nih.gov/pubmed/37333724 http://dx.doi.org/10.1093/ofid/ofad299 |
_version_ | 1785059362688991232 |
---|---|
author | Williams, Frank B Kader, Md Abdul Dickson, Dorothy M Colgate, E Ross Alam, Masud Haque, Rashidul Petri, William A Kirkpatrick, Beth D Lee, Benjamin |
author_facet | Williams, Frank B Kader, Md Abdul Dickson, Dorothy M Colgate, E Ross Alam, Masud Haque, Rashidul Petri, William A Kirkpatrick, Beth D Lee, Benjamin |
author_sort | Williams, Frank B |
collection | PubMed |
description | Breast milk secretor status is associated with antibody seroconversion to oral rotavirus vaccination. Here, we were unable to detect a similar impact on risk of infant rotavirus diarrhea or vaccine efficacy through 2 years of life, underscoring limitations of immunogenicity assessment alone in evaluation of oral rotavirus vaccine response. |
format | Online Article Text |
id | pubmed-10270652 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | Oxford University Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-102706522023-06-16 Maternal Breast Milk Secretor Phenotype Does Not Affect Infant Susceptibility to Rotavirus Diarrhea Williams, Frank B Kader, Md Abdul Dickson, Dorothy M Colgate, E Ross Alam, Masud Haque, Rashidul Petri, William A Kirkpatrick, Beth D Lee, Benjamin Open Forum Infect Dis Brief Report Breast milk secretor status is associated with antibody seroconversion to oral rotavirus vaccination. Here, we were unable to detect a similar impact on risk of infant rotavirus diarrhea or vaccine efficacy through 2 years of life, underscoring limitations of immunogenicity assessment alone in evaluation of oral rotavirus vaccine response. Oxford University Press 2023-06-07 /pmc/articles/PMC10270652/ /pubmed/37333724 http://dx.doi.org/10.1093/ofid/ofad299 Text en © The Author(s) 2023. Published by Oxford University Press on behalf of Infectious Diseases Society of America. https://creativecommons.org/licenses/by/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Brief Report Williams, Frank B Kader, Md Abdul Dickson, Dorothy M Colgate, E Ross Alam, Masud Haque, Rashidul Petri, William A Kirkpatrick, Beth D Lee, Benjamin Maternal Breast Milk Secretor Phenotype Does Not Affect Infant Susceptibility to Rotavirus Diarrhea |
title | Maternal Breast Milk Secretor Phenotype Does Not Affect Infant Susceptibility to Rotavirus Diarrhea |
title_full | Maternal Breast Milk Secretor Phenotype Does Not Affect Infant Susceptibility to Rotavirus Diarrhea |
title_fullStr | Maternal Breast Milk Secretor Phenotype Does Not Affect Infant Susceptibility to Rotavirus Diarrhea |
title_full_unstemmed | Maternal Breast Milk Secretor Phenotype Does Not Affect Infant Susceptibility to Rotavirus Diarrhea |
title_short | Maternal Breast Milk Secretor Phenotype Does Not Affect Infant Susceptibility to Rotavirus Diarrhea |
title_sort | maternal breast milk secretor phenotype does not affect infant susceptibility to rotavirus diarrhea |
topic | Brief Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10270652/ https://www.ncbi.nlm.nih.gov/pubmed/37333724 http://dx.doi.org/10.1093/ofid/ofad299 |
work_keys_str_mv | AT williamsfrankb maternalbreastmilksecretorphenotypedoesnotaffectinfantsusceptibilitytorotavirusdiarrhea AT kadermdabdul maternalbreastmilksecretorphenotypedoesnotaffectinfantsusceptibilitytorotavirusdiarrhea AT dicksondorothym maternalbreastmilksecretorphenotypedoesnotaffectinfantsusceptibilitytorotavirusdiarrhea AT colgateeross maternalbreastmilksecretorphenotypedoesnotaffectinfantsusceptibilitytorotavirusdiarrhea AT alammasud maternalbreastmilksecretorphenotypedoesnotaffectinfantsusceptibilitytorotavirusdiarrhea AT haquerashidul maternalbreastmilksecretorphenotypedoesnotaffectinfantsusceptibilitytorotavirusdiarrhea AT petriwilliama maternalbreastmilksecretorphenotypedoesnotaffectinfantsusceptibilitytorotavirusdiarrhea AT kirkpatrickbethd maternalbreastmilksecretorphenotypedoesnotaffectinfantsusceptibilitytorotavirusdiarrhea AT leebenjamin maternalbreastmilksecretorphenotypedoesnotaffectinfantsusceptibilitytorotavirusdiarrhea |