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Elective Thoracic Aortic Aneurysm Surgery: A Tertiary Center Experience

Background A thoracic aortic aneurysm (TAA) is a diseased expansion of the thoracic aorta. There is morbidity associated with a dilated aorta, as well as significant mortality. Open thoracic surgery is the fundamental management for proximal lesions, offering definitive treatment with excellent resu...

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Autores principales: Badran, Abdul, Elghazouli, Youssef, Shirke, Manasi Mahesh, Al-Tawil, Mohammed, Harky, Amer, Ohri, Sunil K
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10270669/
https://www.ncbi.nlm.nih.gov/pubmed/37332465
http://dx.doi.org/10.7759/cureus.39102
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author Badran, Abdul
Elghazouli, Youssef
Shirke, Manasi Mahesh
Al-Tawil, Mohammed
Harky, Amer
Ohri, Sunil K
author_facet Badran, Abdul
Elghazouli, Youssef
Shirke, Manasi Mahesh
Al-Tawil, Mohammed
Harky, Amer
Ohri, Sunil K
author_sort Badran, Abdul
collection PubMed
description Background A thoracic aortic aneurysm (TAA) is a diseased expansion of the thoracic aorta. There is morbidity associated with a dilated aorta, as well as significant mortality. Open thoracic surgery is the fundamental management for proximal lesions, offering definitive treatment with excellent results. This study aimed to summarize preoperative data and operative outcomes of patients who underwent TAA repair at our institution. Methods Data were retrospectively collected from 234 patients that underwent elective open thoracic surgery at University Hospital Southampton for TAA disease, between 2015 and 2019. Demographics, clinical factors, surgical details, as well as outcome measures, were gathered. Results There were 166 males and 68 females, with an overall mean age of 66 years. The breakdown of operations comprised 105 aortic roots, 171 ascending aorta, 20 aortic arch, and 12 descending aorta cases. The mean follow-up was 370 days. 30-day mortality was 5.13%. Mortality was associated with female gender, aortic root surgery, and prosthetic valves. Mean aortic diameters at the time of surgery for the non-genetic aortopathy and genetic aortopathy groups were respectively 4.93cm and 4.63cm in the aortic root, 5.56cm and 4.88cm in the ascending aorta, 5.08cm and 3.87cm in the aortic arch, and 6.63cm and 5.50cm in the descending aorta. Conclusion Several factors are associated with complications and morbidity, which should be considered when discussing the risks of intervention with patients. There were no neuroprotective strategies that altered post-operative neurological function. Current practice in our unit fits in with current international guidance.
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spelling pubmed-102706692023-06-16 Elective Thoracic Aortic Aneurysm Surgery: A Tertiary Center Experience Badran, Abdul Elghazouli, Youssef Shirke, Manasi Mahesh Al-Tawil, Mohammed Harky, Amer Ohri, Sunil K Cureus Cardiac/Thoracic/Vascular Surgery Background A thoracic aortic aneurysm (TAA) is a diseased expansion of the thoracic aorta. There is morbidity associated with a dilated aorta, as well as significant mortality. Open thoracic surgery is the fundamental management for proximal lesions, offering definitive treatment with excellent results. This study aimed to summarize preoperative data and operative outcomes of patients who underwent TAA repair at our institution. Methods Data were retrospectively collected from 234 patients that underwent elective open thoracic surgery at University Hospital Southampton for TAA disease, between 2015 and 2019. Demographics, clinical factors, surgical details, as well as outcome measures, were gathered. Results There were 166 males and 68 females, with an overall mean age of 66 years. The breakdown of operations comprised 105 aortic roots, 171 ascending aorta, 20 aortic arch, and 12 descending aorta cases. The mean follow-up was 370 days. 30-day mortality was 5.13%. Mortality was associated with female gender, aortic root surgery, and prosthetic valves. Mean aortic diameters at the time of surgery for the non-genetic aortopathy and genetic aortopathy groups were respectively 4.93cm and 4.63cm in the aortic root, 5.56cm and 4.88cm in the ascending aorta, 5.08cm and 3.87cm in the aortic arch, and 6.63cm and 5.50cm in the descending aorta. Conclusion Several factors are associated with complications and morbidity, which should be considered when discussing the risks of intervention with patients. There were no neuroprotective strategies that altered post-operative neurological function. Current practice in our unit fits in with current international guidance. Cureus 2023-05-16 /pmc/articles/PMC10270669/ /pubmed/37332465 http://dx.doi.org/10.7759/cureus.39102 Text en Copyright © 2023, Badran et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Cardiac/Thoracic/Vascular Surgery
Badran, Abdul
Elghazouli, Youssef
Shirke, Manasi Mahesh
Al-Tawil, Mohammed
Harky, Amer
Ohri, Sunil K
Elective Thoracic Aortic Aneurysm Surgery: A Tertiary Center Experience
title Elective Thoracic Aortic Aneurysm Surgery: A Tertiary Center Experience
title_full Elective Thoracic Aortic Aneurysm Surgery: A Tertiary Center Experience
title_fullStr Elective Thoracic Aortic Aneurysm Surgery: A Tertiary Center Experience
title_full_unstemmed Elective Thoracic Aortic Aneurysm Surgery: A Tertiary Center Experience
title_short Elective Thoracic Aortic Aneurysm Surgery: A Tertiary Center Experience
title_sort elective thoracic aortic aneurysm surgery: a tertiary center experience
topic Cardiac/Thoracic/Vascular Surgery
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10270669/
https://www.ncbi.nlm.nih.gov/pubmed/37332465
http://dx.doi.org/10.7759/cureus.39102
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