CK-7 negative primary lung adenocarcinoma

Cytokeratin (CK) 7 is normally expressed in the vast majority of lung adenocarcinoma (ADC). However, on rare occasions, as reported in this paper, CK7 negativity can challenge the diagnosis of pulmonary ADC. Hence, the need to use a combination of ‘immunomarkers’ such as thyroid transcription factor...

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Detalles Bibliográficos
Autores principales: Tchienga, Dimitri, Ascio, Noelani-Mei, Qureshi, Abid, Razia, Sultana, Romulo, Genato, Asarian, Armand, Xiao, Philip, Nouthe, Brice, Belinga, Dominique
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10271213/
https://www.ncbi.nlm.nih.gov/pubmed/37332662
http://dx.doi.org/10.1093/jscr/rjad316
Descripción
Sumario:Cytokeratin (CK) 7 is normally expressed in the vast majority of lung adenocarcinoma (ADC). However, on rare occasions, as reported in this paper, CK7 negativity can challenge the diagnosis of pulmonary ADC. Hence, the need to use a combination of ‘immunomarkers’ such as thyroid transcription factor 1, Napsin A, p40, p63 and CK20.

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