Intranasal Carbetocin Reduces Hyperphagia, Anxiousness, and Distress in Prader-Willi Syndrome: CARE-PWS Phase 3 Trial

CONTEXT: Prader-Willi syndrome (PWS) is a rare genetic disorder characterized by endocrine and neuropsychiatric problems including hyperphagia, anxiousness, and distress. Intranasal carbetocin, an oxytocin analog, was investigated as a selective oxytocin replacement therapy. OBJECTIVE: To evaluate s...

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Detalles Bibliográficos
Autores principales: Roof, Elizabeth, Deal, Cheri L, McCandless, Shawn E, Cowan, Ronald L, Miller, Jennifer L, Hamilton, Jill K, Roeder, Elizabeth R, McCormack, Shana E, Roshan Lal, Tamanna R, Abdul-Latif, Hussein D, Haqq, Andrea M, Obrynba, Kathryn S, Torchen, Laura C, Vidmar, Alaina P, Viskochil, David H, Chanoine, Jean-Pierre, Lam, Carol K L, Pierce, Melinda J, Williams, Laurel L, Bird, Lynne M, Butler, Merlin G, Jensen, Diane E, Myers, Susan E, Oatman, Oliver J, Baskaran, Charumathi, Chalmers, Laura J, Fu, Cary, Alos, Nathalie, McLean, Scott D, Shah, Ajay, Whitman, Barbara Y, Blumenstein, Brent A, Leonard, Sarah F, Ernest, Jessica P, Cormier, Joseph W, Cotter, Sara P, Ryman, Davis C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Clinical Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10271225/
https://www.ncbi.nlm.nih.gov/pubmed/36633570
http://dx.doi.org/10.1210/clinem/dgad015

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