Adoptive T cell transfer and host antigen-presenting cell recruitment with cryogel scaffolds promotes long-term protection against solid tumors

Although adoptive T cell therapy provides the T cell pool needed for immediate tumor debulking, the infused T cells generally have a narrow repertoire for antigen recognition and limited ability for long-term protection. Here, we present a hydrogel that locally delivers adoptively transferred T cell...

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Detalles Bibliográficos
Autores principales: Adu-Berchie, Kwasi, Brockman, Joshua M., Liu, Yutong, To, Tania W., Zhang, David K. Y., Najibi, Alexander J., Binenbaum, Yoav, Stafford, Alexander, Dimitrakakis, Nikolaos, Sobral, Miguel C., Dellacherie, Maxence O., Mooney, David J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10272124/
https://www.ncbi.nlm.nih.gov/pubmed/37322053
http://dx.doi.org/10.1038/s41467-023-39330-7

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