Structural insight into the human SID1 transmembrane family member 2 reveals its lipid hydrolytic activity

The systemic RNAi-defective (SID) transmembrane family member 2 (SIDT2) is a putative nucleic acid channel or transporter that plays essential roles in nucleic acid transport and lipid metabolism. Here, we report the cryo-electron microscopy (EM) structures of human SIDT2, which forms a tightly pack...

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Detalles Bibliográficos
Autores principales: Qian, Dandan, Cong, Ye, Wang, Runhao, Chen, Quan, Yan, Chuangye, Gong, Deshun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10272179/
https://www.ncbi.nlm.nih.gov/pubmed/37322007
http://dx.doi.org/10.1038/s41467-023-39335-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10272179/
https://www.ncbi.nlm.nih.gov/pubmed/37322007
http://dx.doi.org/10.1038/s41467-023-39335-2

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