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Structural insight into the human SID1 transmembrane family member 2 reveals its lipid hydrolytic activity
The systemic RNAi-defective (SID) transmembrane family member 2 (SIDT2) is a putative nucleic acid channel or transporter that plays essential roles in nucleic acid transport and lipid metabolism. Here, we report the cryo-electron microscopy (EM) structures of human SIDT2, which forms a tightly pack...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10272179/ https://www.ncbi.nlm.nih.gov/pubmed/37322007 http://dx.doi.org/10.1038/s41467-023-39335-2 |