A convolutional neural network STIFMap reveals associations between stromal stiffness and EMT in breast cancer

Intratumor heterogeneity associates with poor patient outcome. Stromal stiffening also accompanies cancer. Whether cancers demonstrate stiffness heterogeneity, and if this is linked to tumor cell heterogeneity remains unclear. We developed a method to measure the stiffness heterogeneity in human bre...

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Detalles Bibliográficos
Autores principales: Stashko, Connor, Hayward, Mary-Kate, Northey, Jason J., Pearson, Neil, Ironside, Alastair J., Lakins, Johnathon N., Oria, Roger, Goyette, Marie-Anne, Mayo, Lakyn, Russnes, Hege G., Hwang, E. Shelley, Kutys, Matthew L., Polyak, Kornelia, Weaver, Valerie M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10272194/
https://www.ncbi.nlm.nih.gov/pubmed/37322009
http://dx.doi.org/10.1038/s41467-023-39085-1

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