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Impact of genetic variants within serotonin turnover enzymes on human cerebral monoamine oxidase A in vivo

Variants within the monoamine oxidase A (MAO-A, MAOA) and tryptophan hydroxylase 2 (TPH2) genes, the main enzymes in cerebral serotonin (5-HT) turnover, affect risk for depression. Depressed cohorts show increased cerebral MAO-A in positron emission tomography (PET) studies. TPH2 polymorphisms might...

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Detalles Bibliográficos
Autores principales:	Spies, Marie, Murgaš, Matej, Vraka, Chrysoula, Philippe, Cecile, Gryglewski, Gregor, Nics, Lukas, Balber, Theresa, Baldinger-Melich, Pia, Hartmann, Annette M., Rujescu, Dan, Hacker, Marcus, Winkler-Pjrek, Edda, Winkler, Dietmar, Lanzenberger, Rupert
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10272199/ https://www.ncbi.nlm.nih.gov/pubmed/37322010 http://dx.doi.org/10.1038/s41398-023-02506-2

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