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Bioengineering of bacteria for cancer immunotherapy

Here, we provide a brief overview of the approaches and strategies underlying bacteria-based cancer immunotherapy (BCiT). We also describe and summarize research in the field of synthetic biology, which aims to regulate bacterial growth and gene expression for immunotherapeutic use. Finally, we disc...

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Detalles Bibliográficos
Autores principales: Nguyen, Dinh-Huy, Chong, Ari, Hong, Yeongjin, Min, Jung-Joon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10272223/
https://www.ncbi.nlm.nih.gov/pubmed/37322031
http://dx.doi.org/10.1038/s41467-023-39224-8
Descripción
Sumario:Here, we provide a brief overview of the approaches and strategies underlying bacteria-based cancer immunotherapy (BCiT). We also describe and summarize research in the field of synthetic biology, which aims to regulate bacterial growth and gene expression for immunotherapeutic use. Finally, we discuss the current clinical status and limitations of BCiT.