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Neuronal ApoE4 in Alzheimer’s disease and potential therapeutic targets

The most prevalent genetic risk factor for Alzheimer’s disease (AD) is Apolipoprotein E (ApoE), a gene located on chromosome 19 that encodes three alleles (e2, e3, and e4) that give rise to the ApoE subtypes E2, E3, and E4, respectively. E2 and E4 have been linked to increased plasma triglyceride co...

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Detalles Bibliográficos
Autores principales:	Zhang, Lan, Xia, Yiyuan, Gui, Yuran
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2023
Materias:	Aging Neuroscience
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10272394/ https://www.ncbi.nlm.nih.gov/pubmed/37333457 http://dx.doi.org/10.3389/fnagi.2023.1199434

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