The presence of senescent peripheral T-cells is negatively correlated to COVID-19 vaccine-induced immunity in cancer patients under 70 years of age

PURPOSE: Cancer patients are at risk of severe COVID-19 infection, and vaccination is recommended. Nevertheless, we observe a failure of COVID-19 vaccines in this vulnerable population. We hypothesize that senescent peripheral T-cells alter COVID-19 vaccine-induced immunity. METHODS: We performed a...

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Detalles Bibliográficos
Autores principales: Orillard, E., Spehner, L., Mansi, L., Bouard, A., Falcoz, A., Lepiller, Q., Renaude, E., Pallandre, JR., Vienot, A., Kroemer, M., Borg, C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10272422/
https://www.ncbi.nlm.nih.gov/pubmed/37334387
http://dx.doi.org/10.3389/fimmu.2023.1160664

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