Cargando…
Virus tracking technologies and their applications in viral life cycle: research advances and future perspectives
Viruses are simple yet highly pathogenic microorganisms that parasitize within cells and pose serious threats to the health, economic development, and social stability of both humans and animals. Therefore, it is crucial to understand the dynamic mechanism of virus infection in hosts. One effective...
Autores principales: | , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10272434/ https://www.ncbi.nlm.nih.gov/pubmed/37334362 http://dx.doi.org/10.3389/fimmu.2023.1204730 |
_version_ | 1785059493633064960 |
---|---|
author | Liu, Di Pan, Li Zhai, Huanjie Qiu, Hua-Ji Sun, Yuan |
author_facet | Liu, Di Pan, Li Zhai, Huanjie Qiu, Hua-Ji Sun, Yuan |
author_sort | Liu, Di |
collection | PubMed |
description | Viruses are simple yet highly pathogenic microorganisms that parasitize within cells and pose serious threats to the health, economic development, and social stability of both humans and animals. Therefore, it is crucial to understand the dynamic mechanism of virus infection in hosts. One effective way to achieve this is through virus tracking technology, which utilizes fluorescence imaging to track the life processes of virus particles in living cells in real-time, providing a comprehensively and detailed spatiotemporal dynamic process and mechanism of virus infection. This paper provides a broad overview of virus tracking technology, including the selection of fluorescent labels and virus labeling components, the development of imaging microscopes, and its applications in various virus studies. Additionally, we discuss the possibilities and challenges of its future development, offering theoretical guidance and technical support for effective prevention and control of the viral disease outbreaks and epidemics. |
format | Online Article Text |
id | pubmed-10272434 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | Frontiers Media S.A. |
record_format | MEDLINE/PubMed |
spelling | pubmed-102724342023-06-17 Virus tracking technologies and their applications in viral life cycle: research advances and future perspectives Liu, Di Pan, Li Zhai, Huanjie Qiu, Hua-Ji Sun, Yuan Front Immunol Immunology Viruses are simple yet highly pathogenic microorganisms that parasitize within cells and pose serious threats to the health, economic development, and social stability of both humans and animals. Therefore, it is crucial to understand the dynamic mechanism of virus infection in hosts. One effective way to achieve this is through virus tracking technology, which utilizes fluorescence imaging to track the life processes of virus particles in living cells in real-time, providing a comprehensively and detailed spatiotemporal dynamic process and mechanism of virus infection. This paper provides a broad overview of virus tracking technology, including the selection of fluorescent labels and virus labeling components, the development of imaging microscopes, and its applications in various virus studies. Additionally, we discuss the possibilities and challenges of its future development, offering theoretical guidance and technical support for effective prevention and control of the viral disease outbreaks and epidemics. Frontiers Media S.A. 2023-06-02 /pmc/articles/PMC10272434/ /pubmed/37334362 http://dx.doi.org/10.3389/fimmu.2023.1204730 Text en Copyright © 2023 Liu, Pan, Zhai, Qiu and Sun https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms. |
spellingShingle | Immunology Liu, Di Pan, Li Zhai, Huanjie Qiu, Hua-Ji Sun, Yuan Virus tracking technologies and their applications in viral life cycle: research advances and future perspectives |
title | Virus tracking technologies and their applications in viral life cycle: research advances and future perspectives |
title_full | Virus tracking technologies and their applications in viral life cycle: research advances and future perspectives |
title_fullStr | Virus tracking technologies and their applications in viral life cycle: research advances and future perspectives |
title_full_unstemmed | Virus tracking technologies and their applications in viral life cycle: research advances and future perspectives |
title_short | Virus tracking technologies and their applications in viral life cycle: research advances and future perspectives |
title_sort | virus tracking technologies and their applications in viral life cycle: research advances and future perspectives |
topic | Immunology |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10272434/ https://www.ncbi.nlm.nih.gov/pubmed/37334362 http://dx.doi.org/10.3389/fimmu.2023.1204730 |
work_keys_str_mv | AT liudi virustrackingtechnologiesandtheirapplicationsinvirallifecycleresearchadvancesandfutureperspectives AT panli virustrackingtechnologiesandtheirapplicationsinvirallifecycleresearchadvancesandfutureperspectives AT zhaihuanjie virustrackingtechnologiesandtheirapplicationsinvirallifecycleresearchadvancesandfutureperspectives AT qiuhuaji virustrackingtechnologiesandtheirapplicationsinvirallifecycleresearchadvancesandfutureperspectives AT sunyuan virustrackingtechnologiesandtheirapplicationsinvirallifecycleresearchadvancesandfutureperspectives |