Targeting the PRC2-dependent epigenetic program alleviates urinary tract infections

Urinary tract infection (UTI) is a pervasive health problem worldwide. Patients with a history of UTIs suffer increased risk of recurrent infections, a major risk of antibiotic resistance. Here, we show that bladder infections induce expression of Ezh2 in bladder urothelial cells. Ezh2 is the methyl...

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Detalles Bibliográficos
Autores principales: Guo, Chunming, Zhao, Mingyi, Sui, Xinbing, Balsara, Zarine, Zhai, Songhui, Ahdoot, Michael, Zhang, Yingsheng, Lam, Christa M., Zhu, Ping, Li, Xue
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10272480/
https://www.ncbi.nlm.nih.gov/pubmed/37332606
http://dx.doi.org/10.1016/j.isci.2023.106925

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10272480/
https://www.ncbi.nlm.nih.gov/pubmed/37332606
http://dx.doi.org/10.1016/j.isci.2023.106925

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