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Differential response of C9orf72 transcripts following neuronal depolarization
The (G(4)C(2))(n) nucleotide repeat expansion (NRE) mutation in C9orf72 is the most common genetic cause of ALS and FTD. The biological functions of C9orf72 are becoming understood, but it is unclear if this gene is regulated in a neural-specific manner. Neuronal activity is a crucial modifier of bi...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Elsevier
2023
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10272498/ https://www.ncbi.nlm.nih.gov/pubmed/37332610 http://dx.doi.org/10.1016/j.isci.2023.106959 |