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Promoter hypermethylation of SFRP1 as a prognostic and potentially predictive blood-based biomarker in patients with localized pancreatic ductal adenocarcinoma

INTRODUCTION: Current prognostic blood-based biomarkers for pancreatic adenocarcinoma (PDAC) are limited. Recently, promoter hypermethylation of SFRP1 (phSFRP1) has been linked to poor prognosis in patients with gemcitabine-treated stage IV PDAC. This study explores the effects of phSFRP1 in patient...

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Detalles Bibliográficos
Autores principales:	Stubbe, Benjamin Emil, Larsen, Anders Christian, Madsen, Poul Henning, Krarup, Henrik Bygum, Pedersen, Inge Søkilde, Lundbye-Christensen, Søren, Hansen, Carsten Palnæs, Hasselby, Jane Preuss, Johansen, Astrid Zedlitz, Thorlacius-Ussing, Ole, Johansen, Julia Sidenius, Henriksen, Stine Dam
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2023
Materias:	Oncology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10272559/ https://www.ncbi.nlm.nih.gov/pubmed/37333823 http://dx.doi.org/10.3389/fonc.2023.1211292

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