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Uncovering neuroinflammation-related modules and potential repurposing drugs for Alzheimer's disease through multi-omics data integrative analysis

BACKGROUND: Neuroinflammation is one of the key factors leading to neuron death and synapse dysfunction in Alzheimer's disease (AD). Amyloid-β (Aβ) is thought to have an association with microglia activation and trigger neuroinflammation in AD. However, inflammation response in brain disorders...

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Detalles Bibliográficos
Autores principales: Li, Shensuo, Lu, Changhao, Zhao, Zhenzhen, Lu, Dong, Zheng, Guangyong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10272561/
https://www.ncbi.nlm.nih.gov/pubmed/37333458
http://dx.doi.org/10.3389/fnagi.2023.1161405